Custom Enzymes and Inhibitors
Ubpbio UB ALDEHYDE, 50UG
Ubiquitin Derivatives – Ubiquitin Aldehyde (UBPBio catalog# F3100) – Ub aldehyde is a potent and highly specific inhibitor of cysteine deubiquitinating enzymes including the Ub C-terminal hydrolases (UCHs), the Ub-specific proteases (USPs), the ovarian tumor domains (OTUs) proteases and the Machado-Josephine domain (MJD) proteases. Typical working concentration is 2-5 µM in vitro.
Selleck Chemical LLC Raltitrexed 10mg 112887-68-0 ZD-1694
Raltitrexed (ZD-1694) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC AZD8330 5mg 869357-68-6 ARRY704
AZD8330 (ARRY704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Pazopanib HCl S1035-10mg
Pazopanib HCl is a novel multi-target inhibitor of VEGFR1 VEGFR2 VEGFR3 PDGFR FGFR c-Kit and c-Fms with IC50 of 10 nM 30 nM 47 nM 84 nM 74 nM 140 nM and 146 nM in cell-free assays respectively Pazopanib induces autophagic Type II cell death
Selleck Chemical LLC Barasertib (AZD1152-HQPA) S1147-25mg
Defosbarasertib (AZD1152-HQPA AZD2811 INH-34 Barasertib-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0 37 nM in a cell-free assay 3700 fold more selective for Aurora B over Aurora A Phase 1
Apexbio Technology LLC ICG 001, 10mg. Cas: 847591-62-2 MFCD: MFCD12196918. Wnt/β-catenin pathway inhibitor
Wnt/ Beta -catenin pathway inhibitor blocking Beta -catenin/CBP interaction 847591-62-2. MFCD12196918
Apexbio Technology LLC An ATP-competitive, potent CDK1 inhibitor 872573-93-8. MFCD17392573
An ATP-competitive, potent CDK1 inhibitor 872573-93-8. MFCD17392573
Apexbio Technology LLC Potent, selective, and ATP-competitive CK2 inhibitor 1009820-21-6. MFCD13184796
Potent, selective, and ATP-competitive CK2 inhibitor 1009820-21-6. MFCD13184796
Apexbio Technology LLC Esomeprazole Sodium, 10mg. Cas: 161796-78-7 MFCD: MFCD07802816. Proton pump inhibitor
Esomeprazole sodium (Nexium) is the S-isomer of omeprazole and acts as a proton pump inhibitor. 161796-78-7. MFCD07802816
Apexbio Technology LLC DBeQ, 177355-84-9, MFCD03691820, 10 mg
MF: C22H20N4, MW: 340.42, Solubility: 16mg/mL in DMSO. DBeQ is a selective and reversible inhibitor of p97 ATPase (IC50 = 1.5 uM) which induces caspase-3 and caspase-7 rapidly.
Selleck Chemical LLC AMG-208 10mg 1002304-34-8
AMG 208 is a highly selective dual c-Met and RON inhibitor with IC50 of 9 nM for c-Met. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Didanosine 50mg 69655-05-6
Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 ?M. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC SB216763 5mg 280744-09-4
SB216763 is a potent and selective GSK-3 inhibitor with IC50 of 34.3 nM for GSK-3? and equally effective at inhibiting human GSK-3?. SB216763 activates autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.